|
Significance of positive ANA test in CTD and some non-autoimmune conditions [36] |
|
| Useful for diagnosis |
Useful for monitoring or prognosis |
|
|
|
| 1) Lupus erythmatosus (LE) |
1) Juvenile chronic oligoarticular arthritis |
| SLE |
2) Raynaud phenomenon |
|
|
|
| Discoid LE |
Not useful for diagnosis |
|
|
|
| Subacute cutaneous LE |
|
| Neonatal LE |
1) Relatives of patients with CTD |
| Overlap of two or more LE subsets |
2) Other autoimmune diseases (e.g., Rheumatoid arthritis, Idiopathic thrombocytopenia purpura, primary biliary cirrhosis, autoimmune thyroiditis) |
| Overlap of LE with other CTD |
3) Drugs (e.g., procainamide, hydralazine) |
| 2) SS |
4) Silicone breast implant patients |
| Cutaneous SS (morphea) |
5) Fibromyalgia |
| Systemic SS |
6) Chronic infections |
| a) Limited disease |
7) Neoplasms |
| b) Diffuse disease |
8) Elderly persons |
| 3) PM/Dermatomyositis |
9) Pregnant women |
| 4) Sjögren's syndrome (primary and secondary) |
10) Healthy persons |
| 5) Mixed CTD |
|
| 6) Overlap and undifferentiated CTD |
|
Kumar et al. Diagnostic Pathology 2009 4:1 doi:10.1186/1746-1596-4-1 |
|