Table 5

Cytopathology of Adamantinoma

Author

Age of patient

Site of tumor

Behavior of tumor

Cytologic features


Hales and Ferrell [71]

NA

Tibia

Primary

Peripheral palisading, and prominent extracellular hyaline-like material

Galera-Davidson, et al [72]

31

Tibia

Recurrent

Single-lying cells, small clusters and Indian files, with some nuclear molding. Three cell types (1) large polygonal cells with chromatin clearing, (2) smaller cells with poorly defined cytoplasm and dense chromatin and (3) fusiform cells

Laucirica, et al [73]

25/M

Tibia

Primary

Numerous sheets and single cytologically bland spindle cells with "chromatinic membrane folds"

Perez-Ordonez and Bedard [74]

Two cases

Lung

Metastatic

Small round and spindle cells with indistinct cytoplasm. The nuclei had delicate nuclear membranes, with finely dispersed chromatin and occasional micronucleoli. No pleomorphism.

Tabei, et al [75]

One case

Lung

Metastatic

Clusters of small cells with either prominent nucleoli or spindle-shaped hyperchromatic nuclei.

Flowers et al [76]

One case, 32/M

Tibia, Lung

Recurrent and metastatic

Numerous nuclear membrane grooves within the polygonal cells


NA: Not available

Jain et al. Diagnostic Pathology 2008 3:8   doi:10.1186/1746-1596-3-8

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