Figure 2.

Representative tumors from the morphologically challenging cohort. A, B & C: Photomicrographs of oncocytic tumors (100×). MC20 and MC23 with diagnosis of eosinophilic renal cell carcinomas; MC16 diagnosed as oncocytic renal cell neoplasm, favor chromophobe carcinoma. a, b and c: whole genome view of virtual karyotypes of samples A, B and C respectively. The virtual karyotypes for these tumors show chromosomal patterns consistent with those seen in oncocytomas. The uppermost plot for each sample represents the estimated copy number as a log 2 ratio averaged over 20 SNPs, color-coded Hidden Markov Model (HMM) for copy number (yellow = copy number 2, pink = copy number 3, aqua = copy number 1), color-coded HMM for LOH (yellow = no LOH, blue = LOH).