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Open Access Highly Accessed Case Report

Mucinous breast carcinoma presenting as Paget's disease of the nipple in a man: A case report

Dimitrios Peschos1, Elena Tsanou4, Pavlos Dallas3, Konstantinos Charalabopoulos2*, Christos Kanaris5 and Anna Batistatou3

Author Affiliations

1 Dept. of Forensic Science, Medical Faculty, University of Ioannina, Ioannina, Greece

2 Dept. of Physiology, Clinical Unit, Medical Faculty, University of Ioannina, Ioannina, Greece

3 Dept. of Pathology, Medical Faculty, University of Ioannina, Ioannina, Greece

4 Cytology Laboratory, K Frontzou 7, Ioannina, Greece

5 Gynecologist, C. Tricoupi 6, Ioannina, Greece

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Diagnostic Pathology 2008, 3:42  doi:10.1186/1746-1596-3-42

Published: 24 October 2008

Abstract

Introduction

Male breast cancer is rare compared to its female counterpart representing less than 1% of cancer in men. Moreover, mucinous carcinoma of the male breast is an extremely rare histological subtype of malignancy. Paget's disease of the nipple is rarely observed in males.

Case report

Herein, we describe a unique case of an 86 years old man with mucinous breast cancer presenting as Paget's disease of the nipple. According to the immunohistochemical evaluation the neoplastic cells were positive for estrogen (ER) and progesterone receptors (PR).

Conclusion

To our best knowledge this is the first case of mucinous male breast cancer presenting as Paget's disease of the nipple.