Brightfield double in situ hybridization (BDISH) for HER2 and chromosome 17 centromere (CEN 17) on formalin-fixed, paraffin-embedded clinical breast cancer cases. Examples of normal HER2 gene (A), amplified HER2 gene (B), single HER2 gene (C), and chromosome 17 polysomy (D) cases were shown. 100×.
Nitta et al. Diagnostic Pathology 2008 3:41 doi:10.1186/1746-1596-3-41