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Development of automated brightfield double In Situ hybridization (BDISH) application for HER2 gene and chromosome 17 centromere (CEN 17) for breast carcinomas and an assay performance comparison to manual dual color HER2 fluorescence In Situ hybridization (FISH)

Hiroaki Nitta*, Beatrice Hauss-Wegrzyniak, Megan Lehrkamp, Adrian E Murillo, Fabien Gaire, Michael Farrell, Eric Walk, Frederique Penault-Llorca, Masafumi Kurosumi, Manfred Dietel, Lin Wang, Margaret Loftus, James Pettay, Raymond R Tubbs and Thomas M Grogan

Diagnostic Pathology 2008, 3:41  doi:10.1186/1746-1596-3-41

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