Email updates

Keep up to date with the latest news and content from Diagnostic Pathology and BioMed Central.

Open Access Case Report

Does "ichthyosis uteri" have malignant potential? : A case report of squamous cell carcinoma of endometrium associated with extensive ichthyosis uteri

Kanchan Murhekar1, Urmila Majhi1, V Sridevi2 and T Rajkumar3*

Author affiliations

1 Department of Pathology, Cancer Institute, Adyar, Chennai, India

2 Department of Surgical Oncology, Cancer Institute, Adyar, Chennai, India

3 Department of Molecular Oncology, Cancer Institute, Adyar, Chennai, India

For all author emails, please log on.

Citation and License

Diagnostic Pathology 2008, 3:4  doi:10.1186/1746-1596-3-4

Published: 31 January 2008

Abstract

Ichthyosis uteri is a rare condition in which the entire surface of the endometrium is replaced by stratified squamous epithelium. Though the condition often is considered as benign, anaplastic and dysplastic changes have been reported. We describe herein a rare case of low-grade squamous cell carcinoma of endometrium associated with extensive ichthyosis uteri with dysplasia. The cervix showed moderate to severe dysplastic changes while the right fallopian tube showed extensive squamous metaplasia with dysplastic changes. We conclude that squamous cell carcinoma could develop into pre-existing ichthyosis uteri.