Does

doi:10.1186/1746-1596-3-4

Diagnostic Pathology

Volume 3

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Murhekar K
Majhi U
Sridevi V
Rajkumar T

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Majhi U
Sridevi V
Rajkumar T
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Case Report

Does "ichthyosis uteri" have malignant potential? : A case report of squamous cell carcinoma of endometrium associated with extensive ichthyosis uteri

Kanchan Murhekar¹ , Urmila Majhi¹ , V Sridevi² and T Rajkumar³

¹Department of Pathology, Cancer Institute, Adyar, Chennai, India

²Department of Surgical Oncology, Cancer Institute, Adyar, Chennai, India

³Department of Molecular Oncology, Cancer Institute, Adyar, Chennai, India

author email corresponding author email

Diagnostic Pathology 2008, 3:4doi:10.1186/1746-1596-3-4


Published:	31 January 2008

Abstract

Ichthyosis uteri is a rare condition in which the entire surface of the endometrium is replaced by stratified squamous epithelium. Though the condition often is considered as benign, anaplastic and dysplastic changes have been reported. We describe herein a rare case of low-grade squamous cell carcinoma of endometrium associated with extensive ichthyosis uteri with dysplasia. The cervix showed moderate to severe dysplastic changes while the right fallopian tube showed extensive squamous metaplasia with dysplastic changes. We conclude that squamous cell carcinoma could develop into pre-existing ichthyosis uteri.