Case of a papillary serouscystadenocarcinoma metastasizing to the sigmoid colon. A. Clusters of tumor cells invading the lamina propria and the submucosa. Overlying colonic mucosa is normal. H&E × 200. B. Lymphovascular emboli in the submucosa. H&E × 400. C. IHC results. CK 7 highlighting the tumor cells. DAB × 100. Inset showing higher magnification of CK7 positive tumor cells. DAB × 200. D. Negative CK20. Superficial colonic mucosa showing positivity was an internal positive control. DAB × 100.
Rekhi et al. Diagnostic Pathology 2008 3:39 doi:10.1186/1746-1596-3-39