Figure 1.

Graph illustrating the differences in ethnicity, age and the number of mtDNA sequence variants obtained from three subtypes (serous, endometrioid and micinous) of epithelial ovarian cancer stages using following primers; F 5'-CCACCATCACCCTCCTT-3', and R 5'-CCTACTTGCGCTGCATGTGCC-3' and F 5'-CCCCTCTAGAGCCCACTGTAAAGC-3', R 5'-GTAGTAAGGCTAGGAGGGTG-5; (A), Cumulative frequency of the C7028T variant observed in three subtypes of epithelial ovarian cancer stages; B, ethnic related frequency of C7028T variant observed between African American and Caucasian women with ovarian cancer; C, frequency of T8548G variant among the three subtypes and stages of epithelial ovarian cancer; D, frequency of T8548G variant observed in relation to age between African American and Caucasian women with ovarian cancer; E, electropherogram indicating nucleotide G observed in some of the three epithelial ovarian cancer tissues; F, electropherogram indicating nucleotide T in all the colorectal cancer tissues tested as positive controls; G, frequency of the C9500T variant in relation to stages of the three epithelial ovarian cancer ; H, frequency of the C9500T variant in relation to age between African American and Caucasian women with ovarian cancer.

Aikhionbare et al. Diagnostic Pathology 2008 3:32   doi:10.1186/1746-1596-3-32
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