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Histological variants of cutaneous Kaposi sarcoma

Wayne Grayson1 email and Liron Pantanowitz2 email

Histopathology Department, Ampath National Laboratory Support Services, Johannesburg, South Africa

Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts, USA

author email corresponding author email

Diagnostic Pathology 2008, 3:31doi:10.1186/1746-1596-3-31

Published: 25 July 2008

Abstract

This review provides a comprehensive overview of the broad clinicopathologic spectrum of cutaneous Kaposi sarcoma (KS) lesions. Variants discussed include: usual KS lesions associated with disease progression (i.e. patch, plaque and nodular stage); morphologic subtypes alluded to in the older literature such as anaplastic and telangiectatic KS, as well as several lymphedematous variants; and numerous recently described variants including hyperkeratotic, keloidal, micronodular, pyogenic granuloma-like, ecchymotic, and intravascular KS. Involuting lesions as a result of treatment related regression are also presented.


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