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Clinical data and histology of Medullomyoblastoma |
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| Case No. |
Age#/Sex |
Presentation |
Duration of symptoms (days) |
Imaging (CT/MRI) |
Histopathological features |
|
|
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| 1 |
28 y/M |
Headache, vomiting, ataxic gait |
14 |
Posterior fossa SOL |
Predominant areas of PNE cells, nodules of cells showing smooth muscle differentiation, cartilaginous islands |
| 2 |
6 mon/F |
Vomiting, altered sensorium |
15 |
Posterior fossa SOL, hydrocephalus |
Predominant areas of PNE cells, RMB areas present, focal cartilaginous and epithelial differentiation |
| 3 |
4 y/M |
Recurrent headache, vomiting |
20 |
Posterior fossa contrast enhancing SOL |
Co-dominant RMB and PNE areas, many strap cells present |
| 4 |
3 y/M |
Headache, vomiting, altered sensorium |
20 |
Posterior fossa SOL |
Predominant areas of PNE cells, RMB areas present with strap cells |
| 5 |
4 y/M |
Persistant vomiting |
60 |
Posterior fossa SOL, hydrocephalus |
Predominant areas of PNE cells, RMB areas with strap cells present |
| 6 |
8 y/M |
Headache, vomiting, vertigo |
60 |
Posterior fossa SOL |
Predominant areas comprise of larger atypical cells with vesicular nuclei and moderate amount of cytoplasm, no typical strap cells present, rest of the areas show PNE cells |
| 7 |
4 y/M |
Vomiting, altered sensorium |
30 |
Posterior fossa SOL |
Predominant areas of PNE cells, RMB areas show strap cells |
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PNE – Primitive neuroectodermal; RMB – Rhabdomyoblastic; SOL – Space occupying lesion; Age# y – years & mon-months | |||||
Sachdeva et al. Diagnostic Pathology 2008 3:18 doi:10.1186/1746-1596-3-18 |
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