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Pleomorphic liposarcoma of the foot: a case report

Luka Brčić1, Antonija Jakovčević1, Lovorka Batelja Vuletić1, Dubravko Orlić2 and Sven Seiwerth1*

Author affiliations

1 Institute of Pathology, Medical School, University of Zagreb, Šalata 10, Zagreb, Croatia

2 Department of Orthopedics, Medical School, University of Zagreb, Šalata 6, Zagreb, Croatia

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Citation and License

Diagnostic Pathology 2008, 3:15  doi:10.1186/1746-1596-3-15

Published: 16 April 2008



Liposarcomas are among the most common sarcomas of adult life. Pleomorphic liposarcoma, characterized by pleomorphic lipoblasts, is the rarest subtype. To our knowledge only three cases of pleomorphic liposarcoma of the foot or ankle have been reported so far.

Case presentation

A 71-year-old female presented with a large growing mass on the dorsum of her right foot. Computed tomography showed invasive tumorous mass. Excision biopsy revealed the mass to be a pleomorphic liposarcoma, and below the knee amputation was performed.


Although the incidence of pleomorphic liposarcoma in the foot is very low, it is essential to perform thorough histological analysis of all soft tissue masses, regardless of their benign appearance, because only prompt radical surgery can result in a good prognosis for the patient.