Lymph node biopsy. Follicular destruction was demonstrated with immunohistochemistry, which revealed small clusters of CD10 positive small lymphocytes, corresponding to the residual germinal centers (Upper right panel, original magnification ×400). CD23 immunohistochemistry showed the dendritic cell network to be essentially obliterated (Lower right panel, original magnification ×400). For comparison, normal germinal centers stained for CD10 and CD23 are illustrated in the upper left and lower left panels, respectively (Original magnification ×400).
Hurley et al. Diagnostic Pathology 2008 3:13 doi:10.1186/1746-1596-3-13