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This article is part of the supplement: 35te Tagung der Pathologen am Oberrhein/35th Meeting of Pathologists of the Upper Rhine Region (PATOR) .

Open AccessOral presentation

Induction of distinct gene expression patterns in lymphoid and epithelial cells by the BARF-1 gene of Epstein-Barr virus

A Zur Hausen1, T Wiech1, E Nikolopoulos1, S Lassmann1, T Heidt1, M Sarbia2, A Walch2, M Werner1 and T Ooka3

Institut für Pathologie, Universitätsklinikum Freiburg, Germany

Technische Universität München, Institut für Pathologie, Germany

Université Claude Bernard Lyon, Laboratoire de Virologie Moléculaire, Lyon, France

corresponding author email

from 35te Tagung der Pathologen am Oberrhein/35th Meeting of Pathologists of the Upper Rhine Region (PATOR)
The Institute of Pathology, University Hospital Freiburg, Germany. 1 July 2006

Diagnostic Pathology 2007, 2(Suppl 1):S9doi:10.1186/1746-1596-2-S1-S9

Published: 14 March 2007

First paragraph (this article has no abstract)

The expression of the BARF1 gene of Epstein-Barr virus (EBV) in latent EBV infection is restricted to epithelial malignancies, e.g. gastric carcinomas (GC) or nasopharyngeal carcinomas (NPC). In addition, BARF1 is considered to be a lytic gene because it is expressed upon induction of the lytic cycle in Burkitt's lymphoma cell lines.


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