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This article is part of the supplement: 35te Tagung der Pathologen am Oberrhein/35th Meeting of Pathologists of the Upper Rhine Region (PATOR)

Open AccessOral presentation

Sensitivity of an immunoglobulin heavy chain gene polymerase chain reaction primer system for routine diagnosis of lymphomas

R Heyny-von Haußen, C Braun and G Mall

Pathologisches Institut Klinikum Darmstadt, Darmstadt, Germany

corresponding author email

from 35te Tagung der Pathologen am Oberrhein/35th Meeting of Pathologists of the Upper Rhine Region (PATOR)
The Institute of Pathology, University Hospital Freiburg, Germany. 1 July 2006

Diagnostic Pathology 2007, 2(Suppl 1):S7doi:10.1186/1746-1596-2-S1-S7

Published: 14 March 2007

First paragraph (this article has no abstract)

Polymerase chain reaction (PCR) and length fragment analyses of the immunoglobulin heavy chain (IgH) gene are useful tools for clonality assessment in malignant B-cell-lymphomas and reactive lymphoid infiltrates. The present investigation analyzes the sensitivity of an IgH gene consensus primer multiplex PCR system for the detection of clonality for routine diagnosis in 109 lymphomas during a period of 3 years (2003–2005) at the Institut of Pathology Klinikum Darmstadt.


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