This article is part of the supplement: 35te Tagung der Pathologen am Oberrhein/35th Meeting of Pathologists of the Upper Rhine Region (PATOR)Paraffin tissue microarrays constructed with evenly long paraffin tissue core biopsiesInstitut für Pathologie, Universität Tübingen, Germany
from 35te Tagung der Pathologen am Oberrhein/35th Meeting of Pathologists of the Upper Rhine Region (PATOR) Diagnostic Pathology 2007, 2(Suppl 1):S4doi:10.1186/1746-1596-2-S1-S4
First paragraph (this article has no abstract)Paraffin tissue microarrays (PTMAs) are blocks of paraffin with up to 1,000 paraffin tissue core biopsies (PTCBs). The construction of PTMAs consists of putting PTCBs from so-called donor blocks into preformed holes of so-called recipient blocks, the later PTMAs. Normally, paraffin tissue blocks of daily pathological work are used as donor blocks. However, these blocks have been already cut and contain tissues of different thickness. Therefore, the PTCBs punched out of these paraffin blocks are of different length. In consequence, the sections of the deeper portions of the PTMA don't contain all of the desired PTCBs thereby diminishing the incredible efficacy of the PTMA technique. |




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