Table 1

Comparison Between Immunophenotypes and Ultrastructural Features of Neoplastic Cells in Present Case and Lymphoid Tissue Phagocytic and Accessory Cells Neoplasms*

IM/US**

Case

HS

LCS

IDCS

FDCS


Lysozyme

++

++

+

+

+

CD163

++

N/A

N/A

N/A

N/A

CD68

++

++

+

+

+

S-100

+

+

++

++

+

CD1a

-

-

++

-

-

CD21

-

-

-

-

++

CD23

-

-

-

-

++

EMA

-

-

-

-

+

Fascin

N/A

-

-

-

+

Clusterin

N/A

-

-

-

++

CD45

+

+

+

+

++

CD3

-

-

-

-

-

CD4

+

+

+

-

-

CD20

-

-

-

-

-

MHC II

N/A

+

++

+

-

Lysosomes

Numerous

Numerous

Variable

Scattered

Scattered

Birbeck granules

-

-

++

-

-

Desmosomes

-

-

-

-

++

IDCP***

-

-

-

++

-


* References: 1, 5, 6, 10–12

** IM/US: Immunohistochemical marker/ultrastructure

***IDCP: Interdigitating cell processes

+: weak

++: strong

HS: Histiocytic sarcoma

LCS: Langerhans cell sarcoma

IDCS: Interdigitating dendritic cell sarcoma

FDCS: Follicular dendritic cell sarcoma

Alexiev et al. Diagnostic Pathology 2007 2:7   doi:10.1186/1746-1596-2-7

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