Table 1 |
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|
Comparison Between Immunophenotypes and Ultrastructural Features of Neoplastic Cells in Present Case and Lymphoid Tissue Phagocytic and Accessory Cells Neoplasms* |
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|
IM/US** |
Case |
HS |
LCS |
IDCS |
FDCS |
|
|
|||||
|
Lysozyme |
++ |
++ |
+ |
+ |
+ |
|
CD163 |
++ |
N/A |
N/A |
N/A |
N/A |
|
CD68 |
++ |
++ |
+ |
+ |
+ |
|
S-100 |
+ |
+ |
++ |
++ |
+ |
|
CD1a |
- |
- |
++ |
- |
- |
|
CD21 |
- |
- |
- |
- |
++ |
|
CD23 |
- |
- |
- |
- |
++ |
|
EMA |
- |
- |
- |
- |
+ |
|
Fascin |
N/A |
- |
- |
- |
+ |
|
Clusterin |
N/A |
- |
- |
- |
++ |
|
CD45 |
+ |
+ |
+ |
+ |
++ |
|
CD3 |
- |
- |
- |
- |
- |
|
CD4 |
+ |
+ |
+ |
- |
- |
|
CD20 |
- |
- |
- |
- |
- |
|
MHC II |
N/A |
+ |
++ |
+ |
- |
|
Lysosomes |
Numerous |
Numerous |
Variable |
Scattered |
Scattered |
|
Birbeck granules |
- |
- |
++ |
- |
- |
|
Desmosomes |
- |
- |
- |
- |
++ |
|
IDCP*** |
- |
- |
- |
++ |
- |
|
|
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|
* References: 1, 5, 6, 10–12 ** IM/US: Immunohistochemical marker/ultrastructure ***IDCP: Interdigitating cell processes +: weak ++: strong HS: Histiocytic sarcoma LCS: Langerhans cell sarcoma IDCS: Interdigitating dendritic cell sarcoma FDCS: Follicular dendritic cell sarcoma |
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|
Alexiev et al. Diagnostic Pathology 2007 2:7 doi:10.1186/1746-1596-2-7 |
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