Table 1

Main clinical features of reported CMV oophoritis cases in the English literature

First Author

Age

Menopausal Status

Primary Diagnosis

Prior Immunosuppressive Treatment/State

Documented Systemic CMV infection

Treatment of CMV

Presentatation as Mass lesion

Diagnostic Material


Subietas (1977)

62

Post-menopausal

Astrocytoma

Radiation

Yes (post-mortem)

No

No

Autopsy

Subietas (1977)

40

Post-menopausal

Hodgkin Lymphoma,

Chemotherapy, Steroids, Radiation

Yes (post-mortem)

No

No

Autopsy

Subietas (1977)

67

Post-menopausal

Breast CA

Testosterone, Steroids

No

No

No

Autopsy

Evans (1978)

37

Pre-menopausal

SLE

Steroids

Yes (post-mortem)

No

Yes

Autopsy

LiVolsi (1979)

61

Post-menopausal

Lymphoma

Chemotherapy, Steroids

Yes (post-mortem)

No

No

Autopsy

Iwasaki (1988)

11

Pre-pubertal

ALL

Chemotherapy, Steroids

Yes (pre-mortem)

N/A

No

Autopsy

Williams (1989)

40

Pre-menopausal

Cholangio-CA

Liver Transplant

Yes (post-mortem)

No

Yes

Autopsy

Familiari (1990)

33

Pre-menopausal

AIDS

Anti-retrovirals

Yes (pre-mortem)

Yes

No

Autopsy

Sharma (1994)

50

Post-menopausal

Breast CA

Autologous BMT

No

No

No

Autopsy

Wales (1996)

31

Pre-menopausal

HIV, PID

Anti-retrovirals,

No

No

Yes (limited to left ovary)

Surgical Resection

Nieto (1999)

50

Post-menopausal

Breast CA

Allogenic BMT

Yes (pre-mortem) *

Yes

No

Autopsy

Manfredi (2000)

36

Pre-menopausal

AIDS

Presumed CNS Toxoplasmosis & Lymphoma

No

No

Yes

Autopsy

Current Case (2007)

63

Post-menopausal

Lung CA

Radiation, Steroids

No

No

Yes

Surgical Resection


ALL: acute lymphocytic leukemia; BMT: bone marrow transplantation; CA: carcinoma; CNS: central nervous system; PID: pelvic infectious disease; SLE: systemic lupus erythematosus; N/A: not available; *: pre-mortem systemic CMV infection but post-mortem isolated oophoritis

Yu et al. Diagnostic Pathology 2007 2:50   doi:10.1186/1746-1596-2-50

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