Figure 1.

(A) Tubular adenoma with high-grade dysplasia (H&E, Original magnification × 40). (B) Tubular adenoma with high-grade dysplasia (H&E, Original magnification ×100). (C) Tubular adenoma with adjacent colonic metaplasia (H&E, Original magnification × 40). (D) Both MSH2 (shown) and MLH1 (not shown) demonstrated intact (positive) nuclear staining in the dysplastic ileal epithelium (Immunoperoxidase, Original magnification × 200).