Table 3

Immunohistochemical Results, Tumor Cell Expression

Marker

Thymoma Type


A

AB

B1

B2

B3

MNT


EMA

+

+

Focal

S

+

+

CK7

+

+^

+

+

+

+

CK20

-

-

-

-

-

-

CD57

S

S

S

+*

+*

+

CD5

-

-

-

-

-/+

-

Bcl-2

-

-

-

-

-/+

-

Calretinin

S

S

S

S

S

S

Vimentin

+

+

-

-

-

-

CD20

+

+

-

-

-

-


MNT= micronodular thymoma

S = single cells

+^ = neoplastic epithelial cells in type B component were CK7 negative

-/+ = variably (2 sporadic type B3 thymomas stained strongly positive)

+* = strong expression in type B2 (n = 1) and type B3 (n = 3) thymomas associated with autoimmune disorder; scattered positive neoplastic cells in sporadic thymomas

Alexiev et al. Diagnostic Pathology 2007 2:13   doi:10.1186/1746-1596-2-13

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