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Open Access Highly Accessed Case Report

Glomerulocystic Kidney Disease and its rare associations: an autopsy report of two unrelated cases

Kirti Gupta*, Mahesha Vankalakunti and Man Updesh Singh Sachdeva

Author affiliations

Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India

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Citation and License

Diagnostic Pathology 2007, 2:12  doi:10.1186/1746-1596-2-12

Published: 25 April 2007

Abstract

Background

Glomerulocystic kidney disease is an uncommon type of cystic renal disease. It is characterized by cortical microsysts, which are represented by cystic dilatation of Bowman's spaces.

Case presentation

We describe a case of glomerulocystic disease in a neonate and another in an abortus associated with tracheo-oesophageal fistula and megacystic-megaureter syndrome. The kidney on autopsy was sponge-like and revealed presence of cysts corresponding to dilatations of Bowman's space microscopically. In these two cases, the Glomerulocystic Kidney Disease in one case corresponded to a sporadic form and, in the other, to a syndromic, non-heritable form of glomerulocystic kidney disease.

Conclusion

The associated anomalies in Glomerulocystic Kidney disease are well described in the literature. Two more new unrelated associations are described in this article.