Table 2

Synopsis of all 19 laryngeal inflammatory myofibroblastic tumors published in the English literature.

Patient, Age

Symptoms

Site

CS

Course

Immunostaining

M, 62 [20]

Hoarseness, dysphonia, systemic manifestations (fever and weight loss) for 3 months

True vocal cord

yes

FD 24 months

vim +, actin +, NR: desmin, CK, S100, Alk-1

M, 2 [9]

Snoring, apneic events

Aryepiglottic fold

no

R 7 months

*

F, 52 [11]

Voice change for 12 months

False cord

no

FD 4 years

vim +, sm-actin +, NR: S100, desmin

F, 49 [10]

Dyspnoea, stridor for 4 month, 15 month after road accident

Subglottis

no

Persistence for 1 months after surgery, resurgery with persistence for 12 months, 2^nd resurgery, FD 15 months after resurgery

sm-actin patchy +, NR: desmin, CK, EMA

M, 51 [32]

Hoarseness for 6 months

Vocal cord

*

FD 12 months

vim+, sm-actin+, NR: CK, desmin, S100, CD34

M, 74 [33]

Hoarseness, foreign body sensation, dyspnoe for several months

True vocal cord

*

FD 2 months, death on cardiac failure

vim +, actin +, NR: S100, desmin, CK

M, 57 [34]

Hoarseness, dyspnoe, disphonia for 5 months

Anterior commissur

*

R 2 months, after resurgery FD 12 months

vim +, actin +

M, 72 [35]

Dysphonia for 2 months

True vocal cord

*

FD 6 months

vim +, sm-actin +, CD68 focally +, NR: CK, S100, desmin, CD34, LMP

5 M, 3 F with age median of 59 (19–69) [8]

Hoarseness, stridor, dysphonia, foreign body sensations from 10 days up to 4 months

*

3+/8

7 cases FD, one case with 4 relapses in 24 months

All: vim +, sm-actin +, NR: CK, S100, desmin, myoglobin, CD34

3 further cases, [7]

*

*

*

2 cases FD, one R 12 months

*

Male (M), Female (F), Cigarette smoking (CS +), Free of disease (FD), Recurrence (R), Vimentin (vim), Cytokeratin (CK), positive (+), no reaction (NR), R * not specified or not reported.

Völker et al. Diagnostic Pathology 2007 2:1   doi:10.1186/1746-1596-2-1