Chondrosarcoma of the spine: A rare case with unusual presentation
1 Department of Pathology University of Ioannina Medical School, Ioannina, Greece
2 Department of Neurosurgery, University of Ioannina Medical School, Ioannina, Greece
3 Department of Physiology, Clinical Unit, University of Ioannina Medical School, Ioannina, Greece
Diagnostic Pathology 2006, 1:39 doi:10.1186/1746-1596-1-39Published: 30 October 2006
Chondrosarcoma is the third most common primary malignancy of bone, affecting primarily the pelvic and shoulder girdles and being extremely rare in the spine. Herein, we present a case of a 65-year-old woman with a rare chondrosarcoma of the spine, who presented with clinical symptoms from the lung metastasis. The neoplasm was grade II and exhibited overexpression of the p53 tumor suppressor protein. The latter has been associated with a high propensity for distant metastases.