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A web-based system for tissue microarray data management

Vincenzo Della Mea* 1 email, Irene Bin* 1 email, Maura Pandolfi2 email and Carla Di Loreto* 2 email

1Medical Informatics and telemedicine Lab, Dept. of Mathematics and Computer Science, University of Udine, Italy

2Section of Pathology, Dept. of Medical Morphological Research, University of Udine, Italy

author email corresponding author email* Contributed equally

Diagnostic Pathology 2006, 1:36doi:10.1186/1746-1596-1-36

Published: 11 October 2006

Abstract

Background

Tissue Microarray is a novel technique for analysing large amounts of immunohistochemically stained specimens. However, those large amounts make it difficult to design, prepare and analyze a tissue microarray, so that software support is almost inevitable.

Methods

We designed a tissue microarray data management system starting from specifications obtained by pathologists, and arranged for a preliminary validation in thyroid pathology.

Results

A web-based system has been developed, basing on open-source software and principles, that was well accepted by pathologists and allowed to carry out a study on 52 thyroid pathology cases.

Conclusion

Though limited in functionalities, the developed system is effective and can be downloaded at the address http://mitel.dimi.uniud.it/timan/ webcite.


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