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Melanosis intestini: case report

Anna Batistatou*, John Panelos and Niki J Agnantis

Author Affiliations

Department of Pathology, University of Ioannina Medical School, Ioannina, Greece

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Diagnostic Pathology 2006, 1:3  doi:10.1186/1746-1596-1-3

Published: 31 March 2006


The term melanosis in the gastrointestinal tract refers to the accumulation of pigment deposits in the mucosa. Melanosis of the colon is not uncommon and has been associated with certain conditions, however melanosis of the small intestine is extremely rare. Herein, we describe a case in which we observed melanosis not only in the colon, but in the terminal ileum as well, associated with the use of anthraceneline laxatives. The clinical significance of this condition is not clear, however Gastroenterologists and Pathologists should be aware of its existence.