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Open Access Commentary

Charcot-Leyden crystals in a prostatic adenocarcinoma

Özgür Aydın

Author affiliations

Alanya Hospital, Department of Pathology, Başkent University, Alanya, Antalya, Turkey

Citation and License

Diagnostic Pathology 2006, 1:26  doi:10.1186/1746-1596-1-26

Published: 7 September 2006

Abstract

A transrectal needle biopsy from a 63-year-old man was decided because of a high prostatic spesific antigen in the blood, and a hard right lobe in rectal examination. 10 examples were taken from each lobe. In 1 of 4 of the examples from the left lobe, which contained a small focus of adenocarcinoma, numerous eosinophils were observed to surround the carcinomatous focus and attack the carcinoma cells. Uniquely, at the same focus Charcot-Leyden crystals could be seen in the intraluminal space and stromal area. A carcinoma oriented eosinophil accumulation, and Charcot-Leyden crystals in prostate was not described before.